Crosslinking, Labeling and Protein Modification
Medchemexpress LLC 4-Arm PEG-SCM MW 20 500mg
4-Arm PEG-SCM (MW 20000) is a multi-arm PEG derivative that can be used for peptide modification and drug delivery[1]
eMolecules 1191064-81-9 | FMOC-NH-PEG9-CH2CH2COOH | MFCD28385470 | 1g
1-(5-Bromo-6-methoxy-pyridin-3-yl)-ethanone | Chemcia | 1256837-15-6 | MFCD18258545 | 230.061 | C8H8BrNO2 | 97.000 | COc1ncc(cc1Br)C(C)=O | 1g | 322910615
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eMolecules Building Block Tool
Cayman Chemical PomalIdomIde 4alkylC6amIn 25mg
A PROTAC building block; has been used in the synthesis of PROTACs that drive HDAC8 degradation
Medchemexpress LLC Endo-BCN-PEG4-acid | 1881221-47-1 | 99.3% | 441.52 | C22H35NO8 | 25 MG
Endo-BCN-PEG4-acid is a cleavable four-unit PEG linker containing a bicyclononyne (BCN) group and a terminal carboxylic acid. It is used as a linker in antibody-drug conjugate (ADC) synthesis and as a reagent for strain-promoted alkyne-azide cycloaddition (SPAAC).
- Cleavable 4-unit polyethylene glycol (PEG) linker.
- Contains a BCN group for SPAAC click chemistry.
- Terminal carboxylic acid enables conjugation to amines or alcohols.
- High purity suitable for bioconjugation reactions.
- Colorless to light yellow liquid physical form.
- Long-term storage recommended at -20°C (pure form) or lower when in solution.
Medchemexpress LLC NH2-C5-PEG4-N3-L-lysine-PEG3-N3 | 99.4% | 619.71 | C25H49N9O9 | 50 MG
NH2-C5-PEG4-N3-L-lysine-PEG3-N3 is a cleavable 7-unit PEG antibody-drug conjugate (ADC) linker containing an azide functional group, intended for research use in click chemistry conjugations. It facilitates attachment of payloads to biomolecules via copper-catalyzed azide-alkyne cycloaddition (CuAAC) or strain-promoted azide-alkyne cycloaddition (SPAAC).
- Cleavable 7-unit PEG linker suitable for ADC synthesis.
- Azide functional group for CuAAC and SPAAC click reactions.
- High purity (≈99.4%).
- Water soluble: ≥100 mg/mL.
- Appearance: colorless to light yellow liquid.
- Recommended storage: pure form at -20°C.
- Packaged in 50 mg units.
![eMolecules Folate-PEG-amine, MW 2,000 | Broadpharm |527.542 | C23H29N9O6 | 0.000 | NCCOCCNC(=O)CCC(NC(=O)c1ccc(NCc2cnc3nc(N)[nH]c(=O)c3n2)cc1)C(O)=O | 50mg | 649281325](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502475583.JPG-250.jpg)
eMolecules Folate-PEG-amine, MW 2,000 | Broadpharm |527.542 | C23H29N9O6 | 0.000 | NCCOCCNC(=O)CCC(NC(=O)c1ccc(NCc2cnc3nc(N)[nH]c(=O)c3n2)cc1)C(O)=O | 50mg | 649281325
Folate-PEG-amine, MW 2,000 | Broadpharm |527.542 | C23H29N9O6 | 0.000 | NCCOCCNC(=O)CCC(NC(=O)c1ccc(NCc2cnc3nc(N)[nH]c(=O)c3n2)cc1)C(O)=O | 50mg | 649281325
Cayman Chemical ANTIBODY DBCO-amIn 50mg
A copper-free click chemistry reagent; has been used in the synthesis of clickable fluorescent probes
eMolecules 1609651-90-2 | ChemScene | Alkyne-PEG4-maleimide | 100mg | 686120423 | CS-0118065 | MFCD22380740 | 382.413 | C18H26N2O7
Medchem Express | BAY 2416964 | 5mg | 527574132 | HY-135829 | 2242464-44-2 | 387.820 | C18H18ClN5O3
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eMolecules Building Block Tool<|a>
eMolecules 1835759-82-4 | t-Boc-Aminooxy-PEG3-acid | Broadpharm | MFCD29052175 | 337.369 | C14H27NO8 | 97.000 | CC(C)(C)OC(=O)NOCCOCCOCCOCCC(O)=O | 100mg | 296213224
t-Boc-Aminooxy-PEG3-acid | Broadpharm | 1835759-82-4 | MFCD29052175 | 337.369 | C14H27NO8 | 97.000 | CC(C)(C)OC(=O)NOCCOCCOCCOCCC(O)=O | 100mg | 296213224
STA Pharmaceutical Fmoc-NH-PEG6-CH2CH2COOH | 5 g | CAS 882847-34-9 | MDL MFCD06656474
Fmoc-NH-PEG6-CH2CH2COOH is a Amino Acid reagent (Subcategory: PEG AA) sold by WuXi TIDES. Offered in 5 g. Store at 4 °C. SDS available for reference.
Specifications
- CAS: 882847-34-9
- MDL: MFCD06656474
- InChIKey: HEGZERUHBVYZPH-UHFFFAOYSA-N
- Molecular Weight: 575.655
- Molecular Formula: C30H41NO10
- Purity: ≥95%
- Container Type: 30 mL HDPE
- Pack Size: 5 g
- Net Weight: 5 g
- Gross Weight: 16.5 g
- Commodity Code: 29242970
- Country Of Origin: China
- IUPAC: 1-(9H-fluoren-9-yl)-3-oxo-2,7,10,13,16,19,22-heptaoxa-4-azapentacosan-25-oic acid
- SMILES: O=C(CCOCCOCCOCCOCCOCCOCCNC(OCC1C2=CC=CC=C2C3=CC=CC=C31)=O)O
CCOCCOCCOCCN=[N+]=[N-])C(=O)N[C@@H](CCCNC(N)=O)C(=O)Nc1ccc(COC(=O)Oc2ccc(cc2)[N+]([O-])=O)cc1 | 50mg | 340377065](https://assets.fishersci.com/TFS-Assets/CCG/product-images/NC1655536.jpg-250.jpg)
eMolecules 2055047-18-0 | Azido-PEG3-Val-Cit-PAB-PNP | Broadpharm | MFCD30527416 | 773.801 | C34H47N9O12 | 96.000 | CC(C)[C@H](NC(=O)CCOCCOCCOCCN=[N+]=[N-])C(=O)N[C@@H](CCCNC(N)=O)C(=O)Nc1ccc(COC(=O)Oc2ccc(cc2)[N+]([O-])=O)cc1 | 50mg | 340377065
Azido-PEG3-Val-Cit-PAB-PNP | Broadpharm | 2055047-18-0 | MFCD30527416 | 773.801 | C34H47N9O12 | 96.000 | CC(C)[C@H](NC(=O)CCOCCOCCOCCN=[N+]=[N-])C(=O)N[C@@H](CCCNC(N)=O)C(=O)Nc1ccc(COC(=O)Oc2ccc(cc2)[N+]([O-])=O)cc1 | 50mg | 340377065
Medchemexpress LLC endo-BCN-PEG4-PFP ester | 2904607-26-5 | 95.0% | 607.56 | 50 MG
endo-BCN-PEG4-PFP ester is a PEG-based PROTAC linker primarily used in the synthesis of PROTACs. It functions as a click chemistry reagent, containing a BCN group that facilitates strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules possessing Azide groups. PROTACs are heterobifunctional nanomolecules that comprise two distinct ligands joined by a linker, where one ligand targets an E3 ubiquitin ligase and the other targets a specific protein, leveraging the intracellular ubiquitin-proteasome system for selective protein degradation.
- Functions as a click chemistry reagent
- Contains a BCN group for strain-promoted alkyne-azide cycloaddition (SPAAC)
- Reacts with molecules possessing azide groups
- Utilized in the synthesis of PROTACs
- Leverages the intracellular ubiquitin-proteasome system
- Enables selective degradation of target proteins
![eMolecules Broadpharm / Azide-PEG8-Val-Cit-Doxorubicin / 5mg / 784454862 / BP-29761 / 95.000 / / [null] / 1485.559 / C68H96N10O27](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502473340.JPG-250.jpg)
eMolecules Broadpharm / Azide-PEG8-Val-Cit-Doxorubicin / 5mg / 784454862 / BP-29761 / 95.000 / / [null] / 1485.559 / C68H96N10O27
Broadpharm / Azide-PEG8-Val-Cit-Doxorubicin / 5mg / 784454862 / BP-29761 / 95.000 / / [null] / 1485.559 / C68H96N10O27
